The Association Between Alpha-1 Adrenergic Receptor Antagonists and In-Hospital Mortality From COVID-19

The Association Between Alpha-1 Adrenergic Receptor Antagonists and In-Hospital Mortality From COVID-19

Effective therapies for coronavirus disease 2019 (COVID-19) are urgently needed, and pre-clinical data suggest alpha-1 adrenergic receptor antagonists (α1-AR antagonists) may be effective in reducing mortality related to hyperinflammation independent of etiology. Using a retrospective cohort design...

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Bibliographic Details
Main Authors: Liam Rose, Laura Graham, Allison Koenecke, Michael Powell, Ruoxuan Xiong, Zhu Shen, Brett Mench, Kenneth W. Kinzler, Chetan Bettegowda, Bert Vogelstein, Susan Athey, Joshua T. Vogelstein, Maximilian F. Konig, Todd H. Wagner
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Medicine
Subjects:
COVID-19
coronavirus disease
alpha-1-adrenergic receptor antagonist
infectious disease
off-label drug use
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.637647/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2021.637647/full

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