Using the Bayesian credible subgroups method to identify populations benefiting from treatment: An application to the Look AHEAD trial.

Traditionally, subgroup analyses are used to assess whether patient characteristics moderate treatment effectiveness with general disregard for issues of multiplicity. Using data from The Action for Health in Diabetes (Look AHEAD) trial in the United States, we aim to identify a subgroup where all o...

Full description

Bibliographic Details
Main Authors: Anna Coonan, Patrick Schnell, Joel Smith, John Forbes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0231241