Decreased paraoxonase-1 activity is associated with alterations of high-density lipoprotein particles in chronic liver impairment

<p>Abstract</p> <p>Background</p> <p>Paraoxonase-1 (PON1), a lactonase synthesized by the liver, circulates in blood bound to high-density lipoproteins (HDL). This enzyme is thought to degrade oxidized phospholipids and play an important role in the organism's anti...

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Bibliographic Details
Main Authors: Joven Jorge, Alonso-Villaverde Carlos, Pedro-Botet Juan, Beltrán-Debón Raúl, Rull Anna, Mackness Michael, Mackness Bharti, Aragonès Gerard, Marsillach Judit, Camps Jordi
Format: Article
Language:English
Published: BMC 2010-05-01
Series:Lipids in Health and Disease
Online Access:http://www.lipidworld.com/content/9/1/46