Intestinal CD103+ dendritic cells are key players in the innate immune control of Cryptosporidium parvum infection in neonatal mice.

Cryptosporidium parvum is a zoonotic protozoan parasite found worldwide, that develops only in the gastrointestinal epithelium and causes profuse diarrhea. Using a mouse model of C. parvum infection, we demonstrated by conditional depletion of CD11c+ cells that these cells are essential for the cont...

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Bibliographic Details
Main Authors: Louis Lantier, Sonia Lacroix-Lamandé, Laurent Potiron, Coralie Metton, Françoise Drouet, William Guesdon, Audrey Gnahoui-David, Yves Le Vern, Edith Deriaud, Aurore Fenis, Sylvie Rabot, Amandine Descamps, Catherine Werts, Fabrice Laurent
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3868524?pdf=render