Mechanism of squalene biosynthesis: evidence against the involvement of free nerolidyl pyrophosphate

Several mechanisms that utilize farnesyl pyrophosphate and nerolidyl pyrophosphate as condensing substrates have been postulated for the asymmetric condensation reaction in squalene biosynthesis. Although there is ample evidence that farnesyl pyrophosphate is a substrate for this reaction, there has...

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Bibliographic Details
Main Authors: S.S. Sofer, H.C. Rilling
Format: Article
Language:English
Published: Elsevier 1969-03-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520426665