A potential role for a genetic variation of AKAP5 in human aggression and anger control

The A-kinase-anchoring protein 5 (AKAP5), a post-synaptic multi-adaptor molecule that binds G-protein-coupled receptors (GPCRs) and intracellular signaling molecules has been implicated in emotional processing in rodents, but its role in human emotion and behavior is up to now still not quite clear....

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Main Authors: Sylvia eRichter, Xenia eGorny, Josep eMarco-Pallares, Ulrike M. Krämer, Judith eMachts, Adriana eBarman, Hans-Gert eBernstein, Rebecca eSchüle, Ludger eSchoels, Antoni eRodriguez-Fornells, Carsten eReissner, Torsten eWüstenberg, Hans-Jochen eHeinze, Eckart D Gundelfinger, Emrah eDüzel, Thomas F Münte, Constanze I Seidenbecher, Björn H Schott
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-12-01
Series:Frontiers in Human Neuroscience
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Online Access:http://journal.frontiersin.org/Journal/10.3389/fnhum.2011.00175/full