Micronuclei Formation upon Radioiodine Therapy for Well-Differentiated Thyroid Cancer: The Influence of DNA Repair Genes Variants

Micronuclei Formation upon Radioiodine Therapy for Well-Differentiated Thyroid Cancer: The Influence of DNA Repair Genes Variants

Radioiodine therapy with <sup>131</sup>I remains the mainstay of standard treatment for well-differentiated thyroid cancer (DTC). Prognosis is good but concern exists that <sup>131</sup>I-emitted ionizing radiation may induce double-strand breaks in extra-thyroidal tissues, i...

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Bibliographic Details
Main Authors: Luís S. Santos, Octávia M. Gil, Susana N. Silva, Bruno C. Gomes, Teresa C. Ferreira, Edward Limbert, José Rueff
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Genes
Subjects:
thyroid cancer
Iodine-131
chromosome-defective micronuclei
DNA repair
micronucleus assay
single nucleotide polymorphism
Online Access:https://www.mdpi.com/2073-4425/11/9/1083

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https://www.mdpi.com/2073-4425/11/9/1083

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