Amyloid β and tau pathology in brains of aged pinniped species (sea lion, seal, and walrus)

Amyloid β and tau pathology in brains of aged pinniped species (sea lion, seal, and walrus)

Abstract Alzheimer’s disease (AD) is characterized by the accumulation of amyloid-β (Aβ) as senile plaques and cerebral amyloid angiopathy, and hyperphosphorylated tau (hp-tau) as neurofibrillary tangles in the brain. The AD-related pathology has been reported in several non-human animals, and most...

Full description

Bibliographic Details
Main Authors: Yuta Takaichi, James K. Chambers, Kei Takahashi, Yoshiyuki Soeda, Riki Koike, Etsuko Katsumata, Chiaki Kita, Fuko Matsuda, Makoto Haritani, Akihiko Takashima, Hiroyuki Nakayama, Kazuyuki Uchida
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Acta Neuropathologica Communications
Subjects:
Alzheimer’s disease
Amyloid β
GSK-3β
Tau
Pinniped
Neurodegeneration
Online Access:https://doi.org/10.1186/s40478-020-01104-3

Internet

https://doi.org/10.1186/s40478-020-01104-3

Similar Items