Characterizing the BCG Induced Macrophage and Neutrophil Mechanisms for Defense Against Mycobacterium tuberculosis

Characterizing the BCG Induced Macrophage and Neutrophil Mechanisms for Defense Against Mycobacterium tuberculosis

The live attenuated Mycobacterium bovis strain, Bacille Calmette Guérin (BCG) is a potent innate immune stimulator. In the C57BL/6 mouse model of tuberculosis, BCG vaccination leads to a significant reduction of Mycobacterium tuberculosis burden after aerogenic infection. Our studies indicated that...

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Bibliographic Details
Main Authors: Thomas E. Bickett, Jennifer McLean, Elizabeth Creissen, Linda Izzo, Cassidy Hagan, Antonio J. Izzo, Fabiola Silva Angulo, Angelo A. Izzo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Immunology
Subjects:
innate
BCG—Bacille Calmette-Guérin vaccine
macropahge
mycobacerium tuberculosis
lung
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01202/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01202/full

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