MUC4 overexpression augments cell migration and metastasis through EGFR family proteins in triple negative breast cancer cells.

INTRODUCTION: Current studies indicate that triple negative breast cancer (TNBC), an aggressive breast cancer subtype, is associated with poor prognosis and an early pattern of metastasis. Emerging evidence suggests that MUC4 mucin is associated with metastasis of various cancers, including breast c...

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Main Authors: Partha Mukhopadhyay, Imayavaramban Lakshmanan, Moorthy P Ponnusamy, Subhankar Chakraborty, Maneesh Jain, Priya Pai, Lynette M Smith, Subodh M Lele, Surinder K Batra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3569463?pdf=render