The presence of CXCR4-using HIV-1 prior to start of antiretroviral therapy is an independent predictor of delayed viral suppression.

The emergence of CXCR4-using HIV variants (X4-HIV) is associated with accelerated disease progression in the absence of antiretroviral therapy. However, the effect of X4-HIV variants on the treatment response remains unclear. Here we determined whether the presence of X4-HIV variants influenced the...

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Bibliographic Details
Main Authors: Esther F Gijsbers, Ard van Sighem, Agnes M Harskamp, Matthijs R A Welkers, Frank de Wolf, Kees Brinkman, Jan M Prins, Hanneke Schuitemaker, Angélique B van 't Wout, Neeltje A Kootstra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3787987?pdf=render