Use of Nanovesicles from Orange Juice to Reverse Diet-Induced Gut Modifications in Diet-Induced Obese Mice

Use of Nanovesicles from Orange Juice to Reverse Diet-Induced Gut Modifications in Diet-Induced Obese Mice

We have determined whether orange juice-derived nanovesicles (ONVs) could be used for the treatment of obesity-associated intestinal complications. ONVs were characterized by lipidomic, metabolomic, electron microscopy. In vitro, intestinal barriers (IBs = Caco-2+HT-29-MTX) were treated with ONVs an...

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Bibliographic Details
Main Authors: Emmanuelle Berger, Pascal Colosetti, Audrey Jalabert, Emmanuelle Meugnier, Oscar P.B. Wiklander, Juliette Jouhet, Elisabeth Errazurig-Cerda, Stéphanie Chanon, Dhanu Gupta, Gilles J.P. Rautureau, Alain Geloen, Samir El-Andaloussi, Baptiste Panthu, Jennifer Rieusset, Sophie Rome
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
extracellular vesicles
lipid metabolism
obesity
diet-induced gut modifications
triglycerides
MTP
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050120301753

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http://www.sciencedirect.com/science/article/pii/S2329050120301753

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