1H NMR-based metabolomics investigation of copper-laden rat: a model of Wilson's disease.

Wilson's disease (WD), also known as hepatoleticular degeneration (HLD), is a rare autosomal recessive genetic disorder of copper metabolism, which causes copper to accumulate in body tissues. In this study, rats fed with copper-laden diet are used to render the clinical manifestations of WD, a...

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Bibliographic Details
Main Authors: Jingjing Xu, Huaizhou Jiang, Jinquan Li, Kian-Kai Cheng, Jiyang Dong, Zhong Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4388371?pdf=render