Therapeutic Time Window for Edaravone Treatment of Traumatic Brain Injury in Mice

Traumatic brain injury (TBI) is a major cause of death and disability in young people. No effective therapy is available to ameliorate its damaging effects. Our aim was to investigate the optimal therapeutic time window of edaravone, a free radical scavenger which is currently used in Japan. We also...

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Bibliographic Details
Main Authors: Kazuyuki Miyamoto, Hirokazu Ohtaki, Kenji Dohi, Tomomi Tsumuraya, Dandan Song, Keisuke Kiriyama, Kazue Satoh, Ai Shimizu, Tohru Aruga, Seiji Shioda
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2013/379206