Dietary ω-6 polyunsaturated fatty acid arachidonic acid increases inflammation, but inhibits ECM protein expression in COPD

Dietary ω-6 polyunsaturated fatty acid arachidonic acid increases inflammation, but inhibits ECM protein expression in COPD

Abstract Background The obesity paradox in COPD describes protective effects of obesity on lung pathology and inflammation. However, the underlying relationships between obesity, diet and disease outcomes in COPD are not fully understood. In this study we measured the response to dietary fatty acids...

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Bibliographic Details
Main Authors: Sandra Rutting, Michael Papanicolaou, Dia Xenaki, Lisa G. Wood, Alexander M. Mullin, Philip M. Hansbro, Brian G. Oliver
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Respiratory Research
Subjects:
COPD
ω-6 PUFAs
Airway inflammation
Remodelling
Human pulmonary fibroblasts
Online Access:http://link.springer.com/article/10.1186/s12931-018-0919-4

Internet

http://link.springer.com/article/10.1186/s12931-018-0919-4

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