Prostaglandin F2α-induced Prostate Transmembrane Protein, Androgen Induced 1 mediates ovarian cancer progression increasing epithelial plasticity

Prostaglandin F2α-induced Prostate Transmembrane Protein, Androgen Induced 1 mediates ovarian cancer progression increasing epithelial plasticity

The role of prostaglandin (PG) F2α has been scarcely studied in cancer. We have identified a new function for PGF2α in ovarian cancer, stimulating the production of Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1). We show that this induction increases cell plasticity and proliferation, e...

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Bibliographic Details
Main Authors: Alba Jiménez-Segovia, Alba Mota, Alejandro Rojo-Sebastián, Beatriz Barrocal, Angela Rynne-Vidal, María-Laura García-Bermejo, Raquel Gómez-Bris, Lukas J.A.C. Hawinkels, Pilar Sandoval, Ramon Garcia-Escudero, Manuel López-Cabrera, Gema Moreno-Bueno, Manuel Fresno, Konstantinos Stamatakis
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558619302878

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http://www.sciencedirect.com/science/article/pii/S1476558619302878

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