Dissecting out the complex Ca2+-mediated phenylephrine-induced contractions of mouse aortic segments.

L-type Ca2+ channel (VGCC) mediated Ca2+ influx in vascular smooth muscle cells (VSMC) contributes to the functional properties of large arteries in arterial stiffening and central blood pressure regulation. How this influx relates to steady-state contractions elicited by α1-adrenoreceptor stimulati...

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Bibliographic Details
Main Authors: Paul Fransen, Cor E Van Hove, Arthur J A Leloup, Wim Martinet, Guido R Y De Meyer, Katrien Lemmens, Hidde Bult, Dorien M Schrijvers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4372603?pdf=render