Memantine ameliorates pulmonary inflammation in a mice model of COPD induced by cigarette smoke combined with LPS

Memantine ameliorates pulmonary inflammation in a mice model of COPD induced by cigarette smoke combined with LPS

An enhanced chronic inflammatory response in the airways has been regarded as a critical characteristic of chronic obstructive pulmonary disease (COPD). Memantine, an N-methyl-d-aspartate (NMDA) receptors antagonist, has been reported to alleviate lung inflammation. In this study, we investigated th...

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Bibliographic Details
Main Authors: Qingmei Cheng, Lijuan Fang, Dandan Feng, Siyuan Tang, Shaojie Yue, Yanhong Huang, Jianzhong Han, Jinrong Lan, Wei Liu, Lihua Gao, Ziqiang Luo
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Memantine
Chronic obstructive pulmonary disease (COPD)
Cigarette smoke
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218348315

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http://www.sciencedirect.com/science/article/pii/S0753332218348315

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