American Strain of Zika Virus Causes More Severe Microcephaly Than an Old Asian Strain in Neonatal Mice

Zika virus (ZIKV) has evolved from an overlooked mosquito-borne flavivirus into a global health threat due to its astonishing causal link to microcephaly and other disorders. ZIKV has been shown to infect neuronal progenitor cells of the fetal mouse brain, which is comparable to the first-trimester...

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Bibliographic Details
Main Authors: Feng Zhang, Hong-Jiang Wang, Qin Wang, Zhong-Yu Liu, Ling Yuan, Xing-Yao Huang, Guanghui Li, Qing Ye, Haozhen Yang, Lei Shi, Yong-Qiang Deng, Cheng-Feng Qin, Zhiheng Xu
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396417304188