Technical Evaluation of the COBAS EGFR Semiquantitative Index (SQI) for Plasma cfDNA Testing in NSCLC Patients with EGFR Exon 19 Deletions

The cobas<sup>®</sup> EGFR Test provides a semiquantitative index (SQI) that reflects the proportion of mutated versus wild-type copies of the <i>EGFR</i> gene in plasma. The significance of SQI as an indirect measure of the variant allele frequency (VAF) or mutated copies/mL...

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Bibliographic Details
Main Authors: José Manuel González de Aledo-Castillo, Samira Serhir-Sgheiri, Neus Calbet-Llopart, Ainara Arcocha, Pedro Jares, Noemí Reguart, Joan Antón Puig-Butillé
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Diagnostics
Subjects:
VAF
SQI
Online Access:https://www.mdpi.com/2075-4418/11/8/1319