A phase II trial proposal of total neoadjuvant treatment with primary chemotherapy, stereotactic body radiation therapy, and intraoperative radiation therapy in borderline resectable pancreatic adenocarcinoma

A phase II trial proposal of total neoadjuvant treatment with primary chemotherapy, stereotactic body radiation therapy, and intraoperative radiation therapy in borderline resectable pancreatic adenocarcinoma

Abstract Background The current management guidelines recommend that patients with borderline resectable pancreatic adenocarcinoma (BRPC) should initially receive neoadjuvant chemotherapy. The addition of advanced radiation therapy modalities, including stereotactic body radiation therapy (SBRT) and...

Full description

Bibliographic Details
Main Authors: Salvatore Paiella, Giuseppe Malleo, Nicola Simoni, Renato Micera, Stefania Guariglia, Carlo Cavedon, Giovanni Marchegiani, Alessandro Esposito, Luca Landoni, Luca Casetti, Massimiliano Tuveri, Michele Milella, Erica Secchettin, Gessica Manzini, Chiara Bovo, Matteo De Pastena, Martina Fontana, Roberto Salvia, Renzo Mazzarotto, Claudio Bassi
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Cancer
Subjects:
Intraoperative radiotherapy (IORT)
Pancreatic cancer
Neoadjuvant therapy
Locally advanced pancreatic cancer
Stereotactic body radiation therapy (SBRT)
Online Access:https://doi.org/10.1186/s12885-021-07877-7

Internet

https://doi.org/10.1186/s12885-021-07877-7

Similar Items