Radiosynthesis and Preliminary Biological Evaluation of [F]VC701, a Radioligand for Translocator Protein

Radiosynthesis and Preliminary Biological Evaluation of [F]VC701, a Radioligand for Translocator Protein

Positron emission tomography (PET) can be used to monitor in vivo translocator protein (TSPO) expression by using specific radioligands. Recently, several [ 11 C]PK11195 analogues have been synthesized to improve binding stability and brain availability. [ 18 F]VC701 was synthesized and validated in...

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Bibliographic Details
Main Authors: Giuseppe Di Grigoli, Cristina Monterisi, Sara Belloli, Valeria Masiello, Letterio Salvatore Politi, Salvatore Valenti, Marco Paolino, Maurizio Anzini, Mario Matarrese, Andrea Cappelli, Rosa Maria Moresco
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2015-05-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2015.00007

Internet

https://doi.org/10.2310/7290.2015.00007

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