Radiosynthesis and Preliminary Biological Evaluation of [F]VC701, a Radioligand for Translocator Protein
Positron emission tomography (PET) can be used to monitor in vivo translocator protein (TSPO) expression by using specific radioligands. Recently, several [ 11 C]PK11195 analogues have been synthesized to improve binding stability and brain availability. [ 18 F]VC701 was synthesized and validated in...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi - SAGE Publishing
2015-05-01
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Series: | Molecular Imaging |
Online Access: | https://doi.org/10.2310/7290.2015.00007 |