Alpha-particles induce autophagy in multiple myeloma cells

Alpha-particles induce autophagy in multiple myeloma cells

Objectives: Radiations emitted by the radionuclides in radioimmunotherapy (RIT) approaches induce direct killing of the targeted cells as well as indirect killing through bystander effect. Our research group is dedicated to the development of α-RIT, i.e RIT using α-particles especially for the treat...

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Bibliographic Details
Main Authors: Joelle Marcelle Gaschet, Jean-Baptiste eGorin, Sébastien eGouard, Jérémie eMénager, Alfred eMorgenstern, Frank eBruchertseifer, Alain eFaivre-Chauvet, Yannick eGuilloux, Michel eChérel, François eDavodeau
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Medicine
Subjects:
Autophagy
Multiple Myeloma
Radiobiology
Immunogenicity
Ionizing radiation
bismuth-213
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmed.2015.00074/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmed.2015.00074/full

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