LDx: estimation of linkage disequilibrium from high-throughput pooled resequencing data.

High-throughput pooled resequencing offers significant potential for whole genome population sequencing. However, its main drawback is the loss of haplotype information. In order to regain some of this information, we present LDx, a computational tool for estimating linkage disequilibrium (LD) from...

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Bibliographic Details
Main Authors: Alison F Feder, Dmitri A Petrov, Alan O Bergland
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3494690?pdf=render