Lymphotoxin signaling is initiated by the viral polymerase in HCV-linked tumorigenesis.

Lymphotoxin signaling is initiated by the viral polymerase in HCV-linked tumorigenesis.

Exposure to hepatitis C virus (HCV) typically results in chronic infection that leads to progressive liver disease ranging from mild inflammation to severe fibrosis and cirrhosis as well as primary liver cancer. HCV triggers innate immune signaling within the infected hepatocyte, a first step in mou...

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Bibliographic Details
Main Authors: Yannick Simonin, Serena Vegna, Leila Akkari, Damien Grégoire, Etienne Antoine, Jacques Piette, Nicolas Floc'h, Patrice Lassus, Guann-Yi Yu, Arielle R Rosenberg, Michael Karin, David Durantel, Urszula Hibner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3605200?pdf=render

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http://europepmc.org/articles/PMC3605200?pdf=render

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