Effect of 5-Oxo-2-Pyrrolidinecarboxylic Acid (PCA) as a New Topically Applied Agent for Dry Eye Syndrome Treatment

Effect of 5-Oxo-2-Pyrrolidinecarboxylic Acid (PCA) as a New Topically Applied Agent for Dry Eye Syndrome Treatment

The aim of the study was the evaluation of the suitability of 5-oxo-2-pyrrolidinecarboxylic acid (PCA), also in combination with hyaluronic acid (HA), as artificial tears for treatment of dry eye syndrome (DES). Different aqueous formulations containing 0.10% w/w of PCA were used to determine: (i) e...

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Bibliographic Details
Main Authors: Silvia Tampucci, Daniela Monti, Susi Burgalassi, Eleonora Terreni, Erica Zucchetti, Filippo Baldacci, Patrizia Chetoni
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Pharmaceutics
Subjects:
dry eye
hyaluronic acid
osmoprotectant
5-oxo-2-pyrrolidinecarboxylic acid (PCA)
rabbits
tear fluid
Online Access:http://www.mdpi.com/1999-4923/10/3/137

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http://www.mdpi.com/1999-4923/10/3/137

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