Cyclotron-based production of 68Ga, [68Ga]GaCl3, and [68Ga]Ga-PSMA-11 from a liquid target

Cyclotron-based production of 68Ga, [68Ga]GaCl3, and [68Ga]Ga-PSMA-11 from a liquid target

Abstract Purpose To optimize the direct production of 68Ga on a cyclotron, via the 68Zn(p,n)68Ga reaction using a liquid cyclotron target. We Investigated the yield of cyclotron-produced 68Ga, extraction of [68Ga]GaCl3 and subsequent [68Ga]Ga-PSMA-11 labeling using an automated synthesis module. Met...

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Bibliographic Details
Main Authors: Melissa E. Rodnick, Carina Sollert, Daniela Stark, Mara Clark, Andrew Katsifis, Brian G. Hockley, D. Christian Parr, Jens Frigell, Bradford D. Henderson, Monica Abghari-Gerst, Morand R. Piert, Michael J. Fulham, Stefan Eberl, Katherine Gagnon, Peter J. H. Scott
Format: Article
Language:English
Published: SpringerOpen 2020-11-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Gallium-68
Cyclotron targetry
Positron emission tomography
PSMA
Online Access:http://link.springer.com/article/10.1186/s41181-020-00106-9

Internet

http://link.springer.com/article/10.1186/s41181-020-00106-9

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