Early life exposure to famine and colorectal cancer risk: a role for epigenetic mechanisms.

BACKGROUND:Exposure to energy restriction during childhood and adolescence is associated with a lower risk of developing colorectal cancer (CRC). Epigenetic dysregulation during this critical period of growth and development may be a mechanism to explain such observations. Within the Netherlands Coh...

Full description

Bibliographic Details
Main Authors: Laura A E Hughes, Piet A van den Brandt, Adriaan P de Bruïne, Kim A D Wouters, Sarah Hulsmans, Angela Spiertz, R Alexandra Goldbohm, Anton F P M de Goeij, James G Herman, Matty P Weijenberg, Manon van Engeland
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2776970?pdf=render