A -436C>A polymorphism in the human FAS gene promoter associated with severe childhood malaria.

A -436C>A polymorphism in the human FAS gene promoter associated with severe childhood malaria.

Human genetics and immune responses are considered to critically influence the outcome of malaria infections including life-threatening syndromes caused by Plasmodium falciparum. An important role in immune regulation is assigned to the apoptosis-signaling cell surface receptor CD95 (Fas, APO-1), en...

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Bibliographic Details
Main Authors: Kathrin Schuldt, Cosima C Kretz, Christian Timmann, Jürgen Sievertsen, Christa Ehmen, Claudia Esser, Wibke Loag, Daniel Ansong, Carmen Dering, Jennifer Evans, Andreas Ziegler, Jürgen May, Peter H Krammer, Tsiri Agbenyega, Rolf D Horstmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3098189?pdf=render

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http://europepmc.org/articles/PMC3098189?pdf=render

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