The Effects of Indoxyl Sulfate on Human Umbilical Cord-Derived Mesenchymal Stem Cells In Vitro

The Effects of Indoxyl Sulfate on Human Umbilical Cord-Derived Mesenchymal Stem Cells In Vitro

Background/Aims: Indoxyl sulfate, an important protein-bound uremic toxin, can damage stem cells, thus hampering stem cell-based regenerative medicine approaches targeting chronic kidney diseases (CKD). Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) are thought to have promising clin...

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Bibliographic Details
Main Authors: Wei Wang, Xueyong Liu, Jinghua Li, Yuanyuan Li, Liping Li, Shaohua Wang, Jianchun Zhang, Youkang Zhang, Haichang Huang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
Uremic toxins
Human mesenchymal stem cells
Cellular senescence
CD4+ regulatory T cells
Online Access:http://www.karger.com/Article/FullText/438639

Internet

http://www.karger.com/Article/FullText/438639

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