Preferential effect of isoflurane on top-down versus bottom-up pathways in sensory cortex

Preferential effect of isoflurane on top-down versus bottom-up pathways in sensory cortex

The mechanism of loss of consciousness (LOC) under anesthesia is unknown. Because consciousness depends on activity in the cortico-thalamic network, anesthetic actions on this network are likely critical for LOC. Competing theories stress the importance of anesthetic actions on bottom-up ‘core’ thal...

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Bibliographic Details
Main Authors: Aeyal eRaz, Sean M Grady, Bryan M Krause, Daniel J. Uhlrich, Karen A. Manning, Matthew I Banks
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Systems Neuroscience
Subjects:
Anesthesia
Auditory Cortex
Neocortex
cortical column
auditory evoked response
multimodal integration
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsys.2014.00191/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnsys.2014.00191/full

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