Effects of Maternal Fructose Intake on Perinatal ER-Stress: A Defective XBP1s Nuclear Translocation Affects the ER-stress Resolution

Effects of Maternal Fructose Intake on Perinatal ER-Stress: A Defective XBP1s Nuclear Translocation Affects the ER-stress Resolution

Endoplasmic reticulum (ER) homeostasis is crucial to appropriate cell functioning, and when disturbed, a safeguard system called unfolded protein response (UPR) is activated. Fructose consumption modifies ER homeostasis and has been related to metabolic syndrome. However, fructose sweetened beverage...

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Bibliographic Details
Main Authors: Silvia Rodrigo, María I. Panadero, Elena Fauste, Lourdes Rodríguez, Núria Roglans, Juan J. Álvarez-Millán, Paola Otero, Juan C. Laguna, Carlos Bocos
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Nutrients
Subjects:
fructose
pregnancy
ER stress
methylglyoxal
XBP1s
Online Access:https://www.mdpi.com/2072-6643/11/8/1935

Internet

https://www.mdpi.com/2072-6643/11/8/1935

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