Comparison and optimization of hiPSC forebrain cortical differentiation protocols.

Several protocols have been developed for human induced pluripotent stem cell neuronal differentiation. We compare several methods for forebrain cortical neuronal differentiation by assessing cell morphology, immunostaining and gene expression. We evaluate embryoid aggregate vs. monolayer with dual...

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Bibliographic Details
Main Authors: Christina R Muratore, Priya Srikanth, Dana G Callahan, Tracy L Young-Pearse
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4148335?pdf=render