Macrophage PLTP is atheroprotective in LDLr-deficient mice with systemic PLTP deficiency

Macrophage PLTP is atheroprotective in LDLr-deficient mice with systemic PLTP deficiency

Systemic phospholipid transfer protein (PLTP) is a recognized risk factor for coronary heart disease. In apolipoprotein E-deficient mice, systemic PLTP deficiency is atheroprotective, whereas PLTP overexpression is proatherogenic. As expected, we also observed significantly smaller lesions (P < 0...

Full description

Bibliographic Details
Main Authors: David T. Valenta, Joshua J. Bulgrien, David J. Bonnet, Linda K. Curtiss
Format: Article
Language:English
Published: Elsevier 2008-01-01
Series:Journal of Lipid Research
Subjects:
phospholipid transfer protein
atherosclerosis
bone marrow transplant
inflammation
low density lipoprotein receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520428779

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520428779

Similar Items