Tau reduction in aged mice does not impact Microangiopathy

Tau reduction in aged mice does not impact Microangiopathy

Abstract Microangiopathy, including proliferation of small diameter capillaries, increasing vessel tortuosity, and increased capillary blockage by leukocytes, was previously observed in the aged rTg4510 mouse model. Similar gene expression changes related to angiogenesis were observed in both rTg451...

Full description

Bibliographic Details
Main Authors: Rachel E. Bennett, Miwei Hu, Analiese Fernandes, Marta Perez-Rando, Ashley Robbins, Tarun Kamath, Simon Dujardin, Bradley T. Hyman
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Acta Neuropathologica Communications
Subjects:
Alzheimer’s disease
Blood vessels
Brain microvessels
Tau
Microangiopathy
Neurodegeneration
Online Access:http://link.springer.com/article/10.1186/s40478-020-01014-4

Internet

http://link.springer.com/article/10.1186/s40478-020-01014-4

Similar Items