Embryo and Developmental Toxicity of Cefazolin Sodium Impurities in Zebrafish

Cefazolin sodium is an essential drug that is widely used in clinical therapy for certain infective diseases caused by bacteria. As drug impurities are considered to be one of the most important causes of drug safety issues, we studied embryotoxicity, cardiotoxicity, and neurotoxicity of nine cefazo...

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Bibliographic Details
Main Authors: Bo Chen, Zhu-Qing Gao, Ying Liu, Yang-Min Zheng, Ying Han, Jing-Pu Zhang, Chang-Qin Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00403/full