Gabapentin Prevents Oxaliplatin-Induced Mechanical Hyperalgesia in Mice

Abstract.: Oxaliplatin, a platinum-based chemotherapy drug, frequently causes acute and chronic peripheral neuropathies including mechanical hyperalgesia. These adverse effects hinder anticancer therapy with the drug. In this study, we examined several drugs that might prevent oxaliplatin-induced pe...

Full description

Bibliographic Details
Main Authors: Masahiro Ohsawa, Saki Otake, Tomoyasu Murakami, Shohei Yamamoto, Toshiaki Makino, Hideki Ono
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319301239