The Role of HO-1 and Its Crosstalk with Oxidative Stress in Cancer Cell Survival

Heme oxygenases (HOs) act on heme degradation to produce carbon monoxide (CO), free iron, ferritin, and biliverdin. Upregulation of cellular HO-1 levels is signature of oxidative stress for its downstream effects particularly under pro-oxidative status. Subcellular traffics of HO-1 to different orga...

Full description

Bibliographic Details
Main Authors: Shih-Kai Chiang, Shuen-Ei Chen, Ling-Chu Chang
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/9/2401