Personalized therapy in pediatric high-risk B-cell acute lymphoblastic leukemia

Although cure rates for pediatric acute lymphoblastic leukemia (ALL) have now risen to more than 90%, subsets of patients with high-risk features continue to experience high rates of treatment failure and relapse. Recent work in minimal residual disease stratification and leukemia genomics have incr...

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Bibliographic Details
Main Authors: Seth E. Karol, Ching-Hon Pui
Format: Article
Language:English
Published: SAGE Publishing 2020-06-01
Series:Therapeutic Advances in Hematology
Online Access:https://doi.org/10.1177/2040620720927575