Development of Arteannuin B Sustained-Release Microspheres for Anti-Tumor Therapy by Integrated Experimental and Molecular Modeling Approaches

Development of Arteannuin B Sustained-Release Microspheres for Anti-Tumor Therapy by Integrated Experimental and Molecular Modeling Approaches

Arteannuin B (AB) has been found to demonstrate obvious anti-tumor activity. However, AB is not available for clinical use due to its very low solubility and very short half-life. This study aimed to develop AB long sustained-release microspheres (ABMs) to improve the feasibility of clinical applica...

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Bibliographic Details
Main Authors: Yanqing Wang, Weijuan Huang, Nannan Wang, Defang Ouyang, Lifeng Xiao, Sirui Zhang, Xiaozheng Ou, Tingsha He, Rongmin Yu, Liyan Song
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Pharmaceutics
Subjects:
arteannuin B
microsphere
pharmacokinetics
antitumor activity
PLGA
sustained release
Online Access:https://www.mdpi.com/1999-4923/13/8/1236

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https://www.mdpi.com/1999-4923/13/8/1236

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