Association of eosinophilic inflammation with FKBP51 expression in sputum cells in asthma.

BACKGROUND: Airway eosinophilia is a predictor of steroid responsiveness in steroid-naïve asthma. However, the relationship between airway eosinophilia and the expression of FK506-binding protein 51 (FKBP51), a glucocorticoid receptor co-chaperone that plays a role in steroid insensitivity in asthma...

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Main Authors: Tomoko Tajiri, Hisako Matsumoto, Akio Niimi, Isao Ito, Tsuyoshi Oguma, Hitoshi Nakaji, Hideki Inoue, Toshiyuki Iwata, Tadao Nagasaki, Yoshihiro Kanemitsu, Guergana Petrova, Michiaki Mishima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3675168?pdf=render