Hepatocyte Growth Factor/C-Met Axis in Thyroid Cancer: From Diagnostic Biomarker to Therapeutic Target

The hepatocyte growth factor (HGF)/c-met axis plays a crucial role in cancer development by promoting cellular proliferation, motility, and morphogenesis, as well as angiogenesis. Different cellular distributions of both the ligand and the receptor in benign vs malignant lesions indicate this biolog...

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Bibliographic Details
Main Authors: Maria Trovato, Alfredo Campennì, Salvatore Giovinazzo, Massimiliano Siracusa, Rosaria Maddalena Ruggeri
Format: Article
Language:English
Published: SAGE Publishing 2017-03-01
Series:Biomarker Insights
Online Access:https://doi.org/10.1177/1177271917701126