IL-15 cis Presentation Is Required for Optimal NK Cell Activation in Lipopolysaccharide-Mediated Inflammatory Conditions

IL-15 cis Presentation Is Required for Optimal NK Cell Activation in Lipopolysaccharide-Mediated Inflammatory Conditions

Natural killer (NK) cells have antitumor, antiviral, and antibacterial functions, and efforts are being made to manipulate them in immunotherapeutic approaches. However, their activation mechanisms remain poorly defined, particularly during bacterial infections. Here, we show that upon lipopolysacc...

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Bibliographic Details
Main Authors: Ivan Zanoni, Roberto Spreafico, Caterina Bodio, Marco Di Gioia, Clara Cigni, Achille Broggi, Tatiana Gorletta, Michele Caccia, Giuseppe Chirico, Laura Sironi, Maddalena Collini, Mario P. Colombo, Natalio Garbi, Francesca Granucci
Format: Article
Language:English
Published: Elsevier 2013-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713004622

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http://www.sciencedirect.com/science/article/pii/S2211124713004622

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