Application of Biodegradable Polyhydroxyalkanoates as Surgical Films for Ventral Hernia Repair in Mice

The cytotoxicity and biosafety of poly-(3-hydroxybutyrate) (P3HB) and poly-(3-hydroxybutyrate-co-3-hydroxyvalerate) (P3HBV) films were investigated in vitro using 3T3 fibroblast cells and in vivo through subcutaneous implantation of the film in mice. The in vitro test revealed that endotoxin-free P3...

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Bibliographic Details
Main Authors: Yun Chen, Ya-Hui Tsai, I-Ning Chou, Sheng-Hong Tseng, Ho-Shing Wu
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:International Journal of Polymer Science
Online Access:http://dx.doi.org/10.1155/2014/789681