Ciprofloxacin Enhances TRAIL-Induced Apoptosis in Lung Cancer Cells by Upregulating the Expression and Protein Stability of Death Receptors through CHOP Expression

Ciprofloxacin Enhances TRAIL-Induced Apoptosis in Lung Cancer Cells by Upregulating the Expression and Protein Stability of Death Receptors through CHOP Expression

Ciprofloxacin (CIP) is a potent antimicrobial agent with multiple effects on host cells and tissues. Previous studies have highlighted their proapoptotic effect on human cancer cells. The current study showed that subtoxic doses of CIP effectively sensitized multiple cancer cells to tumor necrosis f...

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Bibliographic Details
Main Authors: Eun Jin Lim, Yu Jeong Yoon, Jeonghoon Heo, Tae Hwa Lee, Young-Ho Kim
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:International Journal of Molecular Sciences
Subjects:
ciprofloxacin
TRAIL
death receptor
CHOP
Online Access:http://www.mdpi.com/1422-0067/19/10/3187

Internet

http://www.mdpi.com/1422-0067/19/10/3187

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