Differences in inflammation and acute phase response but similar genotoxicity in mice following pulmonary exposure to graphene oxide and reduced graphene oxide.

Differences in inflammation and acute phase response but similar genotoxicity in mice following pulmonary exposure to graphene oxide and reduced graphene oxide.

We investigated toxicity of 2-3 layered >1 μm sized graphene oxide (GO) and reduced graphene oxide (rGO) in mice following single intratracheal exposure with respect to pulmonary inflammation, acute phase response (biomarker for risk of cardiovascular disease) and genotoxicity. In addition, we as...

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Bibliographic Details
Main Authors: Stefan Bengtson, Kristina B Knudsen, Zdenka O Kyjovska, Trine Berthing, Vidar Skaug, Marcus Levin, Ismo K Koponen, Abhay Shivayogimath, Timothy J Booth, Beatriz Alonso, Amaia Pesquera, Amaia Zurutuza, Birthe L Thomsen, Jesper T Troelsen, Nicklas R Jacobsen, Ulla Vogel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5453440?pdf=render

Internet

http://europepmc.org/articles/PMC5453440?pdf=render

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