NF-κB oscillations translate into functionally related patterns of gene expression

NF-κB oscillations translate into functionally related patterns of gene expression

Several transcription factors (TFs) oscillate, periodically relocating between the cytoplasm and the nucleus. NF-κB, which plays key roles in inflammation and cancer, displays oscillations whose biological advantage remains unclear. Recent work indicated that NF-κB displays sustained oscillations th...

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Bibliographic Details
Main Authors: Samuel Zambrano, Ilario De Toma, Arianna Piffer, Marco E Bianchi, Alessandra Agresti
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-01-01
Series:eLife
Subjects:
synchronous oscillations
NF-kappaB
TNF-alpha
transcription
mathematical modelling
single-cell imaging
Online Access:https://elifesciences.org/articles/09100

Internet

https://elifesciences.org/articles/09100

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