Mitofusin-2 mediates doxorubicin sensitivity and acute resistance in Jurkat leukemia cells

Mitofusin-2 mediates doxorubicin sensitivity and acute resistance in Jurkat leukemia cells

Mitochondria oscillate along a morphological continuum from fragmented individual units to hyperfused tubular networks. Their position at the junction of catabolic and anabolic metabolism couples this morphological plasticity, called mitochondrial dynamics, to larger cellular metabolic programs, whi...

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Bibliographic Details
Main Authors: Carl W. Decker, Jerome Garcia, Kristelle Gatchalian, Deronisha Arceneaux, Clarice Choi, Si Cave, Derick Han, Jeniffer B. Hernandez
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Biochemistry and Biophysics Reports
Subjects:
Mitochondrial fusion
Doxorubicin
MFN-2
Sensitivity
OXPHOS
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580820301345

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http://www.sciencedirect.com/science/article/pii/S2405580820301345

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