Expression of peroxisome proliferator-activated receptor (PPAR)-α and PPAR-γ in the lung tissue of obese mice and the effect of rosiglitazone on proinflammatory cytokine expressions in the lung tissue

Expression of peroxisome proliferator-activated receptor (PPAR)-α and PPAR-γ in the lung tissue of obese mice and the effect of rosiglitazone on proinflammatory cytokine expressions in the lung tissue

PurposeWe investigated the mRNA levels of peroxisome proliferator-activated receptor (PPAR)-α, PPAR-γ, adipokines, and cytokines in the lung tissue of lean and obese mice with and without ovalbumin (OVA) challenge, and the effect of rosiglitazone, a PPAR-γ agonist.MethodsWe developed 6 mice models:...

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Bibliographic Details
Main Authors: Seung Lok Ryu, Jae Won Shim, Duk Soo Kim, Hye Lim Jung, Moon Soo Park, Soo-Hee Park, Jinmi Lee, Won-Young Lee, Jung Yeon Shim
Format: Article
Language:English
Published: Korean Pediatric Society 2013-04-01
Series:Korean Journal of Pediatrics
Subjects:
Peroxisome proliferator-activated receptors
Obesity
Transforming growth factor-beta
Vascularendothelial growth factor
Tumor necrosis factor-alpha
Online Access:http://kjp.or.kr/upload/pdf/kjped-56-151.pdf

Internet

http://kjp.or.kr/upload/pdf/kjped-56-151.pdf

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